Journal of Clinical Case Reports

Primary Cutaneous Diffuse Large B-Cell Lymphoma with Tongue Involvement

Abstract

Satoshi Kayukawa, Takae Kataoka, Tomoko Nishio, Takashi Kanamori, Takaki Kikuchi, Ryuichi Furuta and Kenji Ina

We report a case of diffuse large B-cell lymphoma involving the thigh skin and tongue in an 85-year-old woman. No systemic symptoms or other lesions were observed at diagnosis. Local radiotherapy was effective, but cutaneous recurrence occurred 6 months after the treatment. The patient died of old age with no macroscopically distinguishable nodal or systemic lesions. A postmortem examination revealed intravascular invasion into the tongue, lung, and lymph nodes around the pancreas. To our knowledge, this is the first report of primary cutaneous diffuse large B-cell lymphoma with tongue involvement.