Immune-mediated glomerular diseases encompass a diverse group
of kidney disorders characterized by immune system dysfunction leading
to glomerular inflammation, damage, and eventual loss of renal function.
These diseases include conditions such as lupus nephritis, IgA nephropathy,
membranous nephropathy, and ANCA-associated vasculitis, all of which pose
significant challenges in treatment due to their complex pathophysiology.
Traditional therapeutic approaches have relied on broad immunosuppressive
strategies, but recent advances in multitarget therapy have revolutionized
the management of these conditions by providing more effective and less
toxic treatment options.
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