Journal of Clinical Case Reports

Pyoderma Gangrenosis Complicated with Multiple Cavitary Pulmonary Abscesses: A Case Report and Review of the Literature

Abstract

Zhang L and Wang P

Pyoderma Gangrenosum (PG) is an ulcerating, idiopathic, neutrophilic, non-infective inflammatory disease that primarily affects the skin. Pulmonary manifestations are uncommon. The most important differential diagnoses are pneumonia, lung cancer, lung abscess, and Wegener’s granulomatosis. Here, we present a case with fever, cough, and cutaneous lesion, which was initially misdiagnosed as pneumonia. A CT scan showed irregular cavitated consolidation in both lower lungs. Histopathological skin findings were non-specific. The skin and lung lesions rapidly improved with corticosteroid treatment. This case demonstrates the challenges in the diagnosis of PG with lung involvement.