Nuclear Medicine & Radiation Therapy

Role of MR Apparent Diffusion Coefficient in Characterization of Cystic Renal Masses Using 3T MRI

Abstract

Zahra A Saly, Abou El Ghar Mohamed, Refaat Medhat and Elasaaed Mohamed

Now it is more than 30 years since we are using the Bosniak classification for cystic renal masses, which represents the scale for cancer probability using imaging features. First, we used ultrasound, then CT then MRI for characterization.

Many studies were conducted try to characterize the lesions using the ADC values trying to reach solid values for characterization and subgrouping which we can use especially for indeterminate lesions and for benign lesions which are radiologically characterized as Bosniak III and IV and underwent unnecessary nephrectomies.

Objectives: Retrospective evaluation the efficiency of DWI and ADC values in characterization of benign, indeterminate, and malignant renal masses using 3T MRI.
Results: We found the ADC values of the benign cysts are significantly higher than malignant cysts (3.03 versus 2.35 10 mm/s), Median, P=0.0001 with sensitivity and specificity 84% and 92%, however still no definite cut off values for indeterminate lesions.
Conclusion: MRI ADC values can be used for differentiation of benign and malignant lesions with high sensitivity and specificity however still no definite cut off values for radiologically indeterminate cystic renal masses.

 

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