Journal of Nephrology & Therapeutics

Serum Electrolyte Disturbances in Benign Prostate Hyperplasia after Transurethral Resection of the Prostate

Abstract

Javed Altaf *,Adeel Hyder Arain ,Bikha Ram Devrajani ,Saira Baloch

Objectives: The objective of this study was to determine the frequency of serum electrolyte disturbances in patients with benign prostate hyperplasia after transurethral resection of the prostate.

Material and Methods: The cross sectional and descriptive study was carried out at the department of urology, Liaquat university hospital Jamshoro/Hyderabad. An informed consent was taken from all patients who were diagnosed as benign prostate hyperplasia in the department of urology by consultant urologist. All such patients were assessed for their serum electrolytes plstoperatively (on the first postoperative day) by taking 3cc venous blood sample in a sterilized disposable syringe and send to laboratory for analysis. The data were collected on pre-designed proforma.

Results: The mean age ± SD (range) was 61.25 years ± 8.86 (50 to 90 years). Most of the patients i.e. 44 (29.3%, n=150) were between were seen in the age group 61 to 65 years. 57(38.0%) patients had the frequency of electrolyte disturbance. Mean preoperative and postoperative Hyponatremia was (129.29 ± 1.94) mmol/L and (132.05 ± 2.41) mmol/L (P>0.0001) whereas mean preoperative and postoperative Hypernatremia was (149.8 ± 0.3) mmol/L and (147.2 ± 1.1) mmol/L (P>0.02). Mean preoperative and postoperative Hypochloremia was (2.82 ± 0.5) mmol/L and (3.8± 1.6) mmol/L (P>0.03) whereas mean preoperative and postoperative Hyperkalemia was (110 ± 12.5) mmol/L and (106 ± 9.5) mmol/L (P>0.04). Mean preoperative and postoperative Hypochloremia was (80.0 ± 10.6) mmol/L and (95.0 ± 11.2) mmol/L (P>0.0001) whereas mean preoperative and postoperative Hyperchloremia was (130 ± 7.6) mmol/L and (110 ± 9.6) mmol/L (P>0.05). Mean preoperative and postoperative sodium bicarbonate (HCO3) at lower was (20.0± 1.4) mmol/L and (29.0 ± 2.1) mmol/L (P>0.002) and mean preoperative and postoperative Hyperchloremia was (38.1 ± 2.5) mmol/L and (31.02 ± 3.6) mmol/L (P>0.006).

Conclusion: The further research should be required in advance and extended phase at different and wide clinical setting to gives more and better knowledge related to electrolyte disturbances in transurethral resection of prostate.