Solid organ transplant recipients are at an increased risk of developing skin cancer due to long-term immunosuppressive medication use. This review explores the complex relationship between immunity, immunosuppressive drugs and the occurrence of Non-Melanoma Skin Cancers (NMSCs) in transplant recipients. We analyze key factors affecting skin cancer risk, including type and dosage of immunosuppressive medications, as well as individual patient characteristics. The literature review suggests that achieving a delicate balance between preventing graft rejection and reducing skin cancer risk is a challenge. We discuss strategies for mitigating NMSC risk, such as the use of alternative immunosuppressive regimens and vigilant dermatological monitoring. Ultimately, a multidisciplinary approach is required to ensure the overall well-being of transplant recipients.
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Transplantation Technologies & Research received 223 citations as per Google Scholar report