Vimla Kumari, Kamini Kaushal, Ashwini K Sharma, Rajesh Chandra Mishra and Pradeep Soni
In the last few decades, phytochemicals have potentially gained as an important place in cancer research. The interests for these compounds have grown by researchers, as these compounds have natural in origin and hence, no stipulated side effects are known. Currently, thousands of natural herbs based compounds have been screened for their novel efficiency to control cancer cell proliferation. Among these, a large number of natural compounds gained high preventive and therapeutic values against cancer and most potential compounds along of the are lupeol, saponins, flavanoids, curcumin, resveratrol, geneistein, gingerol, allyl sulfide, berberine, lycopene, bromelain, indole-3-carbinol and polyphenols. The recent research on phytochemicals towards evaluating the anticancer efficacy has been accelerated by development of biophysical technologies. However, several challenges still persist in cancer research like heterogeneity, development of novel phenotypes in cancer cell by therapeutic drugs and tumour recurrence. These challenges open a new dimension for cancer research, and also give weightage to explore the uses of specific phytochemicals in therapy. This review summarizes the latest research in cancer treatment using the bioactive components from medicinal plants.
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