GET THE APP

..

Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

Open Access

Standard WT1 Expression Using Immunohistochemistry

Abstract

Shigetaka Shimodaira, Koichi Hirabayashi, Terutsugu Koya, Yumiko Higuchi and Kenji Sano

Although it remains difficult to treat advanced cancers affecting organs with distant metastasis, therapeutic cancer vaccination is conducted for the induction of an efficient immune response against tumor-associated antigens. Wilms’ tumor 1 (WT1) shown to be the most potent tumor-associated antigens may have potentially strong therapeutic activity against cancers. WT1 expression using immunohistochemistry (IHC) can be evaluated on paraffin-embedded tissues and is proportional to mRNA levels. The standardized IHC would be useful for personalized cancer immunotherapy.

PDF

Share this article

Google Scholar citation report
Citations: 2054

Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report

Molecular Biomarkers & Diagnosis peer review process verified at publons

Indexed In

 
arrow_upward arrow_upward