Nuclear Medicine & Radiation Therapy

Stereotactic Body Radiotherapy (Sbrt) for Oligometastases

Abstract

José Luis López Guerra

Cancer range between disease that remains local throughout its course and disease that is already systemic at the time of diagnoses (spectrum hypothesis). Successful metastatization is a complex interation between the tumor cells, tumor microenvironment, and host. For a tumor cell to acquire the ability to colonize a distant organ, genetic and epigenetic changes in expression are required.