Journal of General Practice

Steven Johnson Syndrome: Adverse Drug Reaction

Abstract

Chandaluri P, Prabhanjan M

The Steven-Johnson Syndrome (SJS) is a rare immune complex mediated hypersensitivity condition. Here we report the case of Steven-Johnson Syndrome due to the co-administration of aceclofenac and cefixime. NSAIDs are the rare type of medication that causes SJS and cefixime is a traditional medication that causes the condition. A 22- years-old patient was admitted in the hospital with a complaint of fever for 15 days and he was treated by giving aceclofenac, cefixime and general symptomatic treatment. On the 4th day of treatment erythromatous patches were observed throughout the body. Laboratory investigations were performed and the case was identified as Steven-Johnson Syndrome. The treatment was withdrawn and he was administered with steroids, amoxicillin, metronidazole and general symptomatic treatment. The patient has recovered after a week.