Lazhar Bechki, Lounes A, Chouirfat K, Bechki MK and Kadri M
Imidazole is a heterocyclic compound a five-membered of diunsaturated cyclic the structure composed of atoms three carbon and two atoms nitrogen in non-adjacent positions. The simplest member of the family is imidazole itself, colorless to pale yellow crystalline solid yellow with a faint odor amine like, soluble in water and alcohol, melts at 89°C to 256°C. After Imidazole’s are poorly soluble in water in general, but are dissolved in organic solvents such as chloroform, propylene glycol and polyethoxylated castor oil. Imidazole’s have antibacterial, antifungal, antiprotozoal, and anthelmintic. Several distinct phenylimidazoles are therapeutically useful as antifungal agents against superficial infections or systemic be. Thiabendazoles that deworming and anti-fungal properties are compounds of the imidazole class. Benzimidazole is a bicyclic compound having an imidazole ring fused to the benzene. The Benzimidazole structure is a part of the portion of the nucleotide vitamin B12 and the core in some drugs, such as inhibitors of the proton pump and anthelmintic agents. Imidazole has two nitrogen atoms. One is slightly acidic, while the other is at the bottom. The imidazole and its derivatives are widely used as intermediates in the synthesis of biological target or pharmaceutical compounds, agrochemicals, dyes, photographic chemicals, corrosion inhibitors, curing agents for epoxy resin adhesives and plastic modifiers.
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