Numerous diseases, including cancer, functional illnesses like chronic fatigue syndrome and fibromyalgia, cardiometabolic conditions like coronary artery disease, hypertension, heart failure and diabetes, among others, are preventable in secondary, primary and primordial ways with regular exercise. Regular exercise has also been demonstrated to lower the risk of physical dependency and impairment, as well as mortality from all causes, happiness and lifespan. It is particularly interesting because cardiorespiratory fitness is now regarded as a substantial quantitative predictor of all-cause mortality and may be a more accurate predictor of death than recognised risk variables. Clinically, the biggest documented reduction in mortality is shown when a patient's cardiorespiratory fitness is raised from a low level (ability to complete an activity between six and eight METs) to a moderate level (capacity to perform an exercise between six and eight METs). Lean body mass and lifespan are also shown to be positively correlated, especially in individuals with low body mass index (BMI); low muscle mass was more strongly and substantially connected with all-cause death than was poor muscular strength.
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