Gaddam Lakshmi Teja, Donthamsetty Venkata Sowmya, Adivireddy Padmaja, Vasikarla Kamala Prasad and Venkatapuram Padmavathi
Pyrazolyl triazoles (5) were prepared by 1,3-dipolar cycloaddition of diazomethane to Schiff base - 3-ethynyl- N-(heteroarylmethylene)aniline (3), followed by oxidation with I2 in DMSO and studied their antimicrobial activity. The pyridine and dichloropyridine substituted compounds 3d, 5c and 5d are potential antibacterial agents against Bacillus subtilis and 3d is a potential antifungal agent against Penicillium chrysogenum.
PDFShare this article
Medicinal Chemistry received 6627 citations as per Google Scholar report