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Medicinal Chemistry

ISSN: 2161-0444

Open Access

Synthesis and Antimicrobial Activity of Some Novel N-Mannich Bases of Imidazole Phenylazetidin-2-one

Abstract

Esther Rani V and Kanderi Dileep Kumar

The novel derivative of β-lactams of Imidazolephenylazetidin-2-ones 7(a-h) are an important class of heterocycles, having potential biological importance due to their unique features. The process of convert of imine (Schiffs base) to azetidine (β-lactam) through an intermediate of monochloro acetyl chloride is important synthetic method for preparation of azetidine-2-ones.

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