Medicinal Chemistry

Synthesis and Characterization of Bromoclenbuterol

Abstract

Ravi Kumar Kannasani, Srinivasa Reddy Battula, Suresh Babu Sannithi, Sreenu Mula and Venkata Babu VV

Clenbuterol is a sympathomimetic amine used for breathing disorders as a decongestant and bronchodilator. During the process development of clenbuterol, the process related impurity bromoclenbuterol was identified as a critical impurity along with the final API. The present work describes the synthesis and characterization of this bromoclenbuterol.