Medicinal Chemistry

Synthesis, Characterization and Antioxidant Activity of Carvacrol Based Sulfonates

Abstract

Suresh D Bagul, Jamatsing D Rajput, Manohar M Patil and Ratnamala S Bendre

In the present investigation, we report eight novel benzenesulfonate derivatives of carvacrol prepared by using sulfonyl chlorides and carvacrol. Their structures were investigated on the basis of modern sophisticated analytical techniques such as 1H and 13C NMR, LC-MS and FT-IR spectroscopy. The synthesized derivatives are screened for their antioxidant test by DPPH radical scavenger assay. Among the tested compounds, 6g and 6h have emerged as better antioxidants.