Maxillofacial bone tissue engineering stands at the forefront of revolutionary advancements in regenerative medicine, offering hope for improved outcomes in facial reconstruction and repair. However, the design of scaffolds for this intricate application requires special considerations. This article explores the challenges faced in the design of scaffolds for maxillofacial bone tissue engineering, emphasizing the pressing need for improvements in clinically available scaffolds. The discussion encompasses current limitations, ongoing research endeavors, and potential pathways to elevate the efficacy of maxillofacial bone repair. The reconstruction of maxillofacial bone defects poses unique challenges that demand specialized solutions in tissue engineering.
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