Journal of Clinical Case Reports

The Efficacy of Chemotherapy against Metastatic Malignant Phyllodes Tumors of the Breast

Abstract

Bourhafour Mouna, Belbaraka Rhizlane, Saber Boutayeb and Hassan Errihani

Phyllodes tumours are rare neoplasms of the female breast. Ten-year survival of 42% is reported after surgical treatment of malignant phyllodes tumours. Metastatic tumours have a poor prognosis with no long-term survival. We present the case history of a 43 year old woman with a pulmonary metastasis from a malignant phyllodes tumour of the breast treated with chemotherapy. The role of radiation therapy and chemotherapy is not established and has not been studied in randomized trials due to the rarity of the tumor. At present, there is no consensus that patients with high-grade phyllodes tumors of the breast will benefit from either of these modalities.