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Journal of Interventional and General Cardiology

ISSN: 2684-4591

Open Access

The Evolving Role of Coronary Micro Vascular Dysfunction in Heart Failure with Preserved Ejection Fraction

Abstract

Daniel Martinez*

Heart failure with preserved ejection fraction (HFpEF) has become an increasingly recognized form of heart failure, accounting for a significant proportion of heart failure cases, particularly in older adults and those with comorbidities such as hypertension, diabetes, and obesity. Unlike heart failure with reduced ejection fraction (HFrEF), where systolic dysfunction is the primary mechanism, HFpEF is characterized by a preserved left ventricular ejection fraction (LVEF) but impaired diastolic function, resulting in symptoms of heart failure. One of the key pathophysiological features of HFpEF is Coronary Microvascular Dysfunction (CMD), a condition where the small coronary arteries fail to properly regulate blood flow to the heart muscle, leading to inadequate myocardial perfusion despite a normal or near-normal epicardial coronary artery structure.

Received: 02 September, 2024, Manuscript No. ; Editor Assigned: 04 September, 2024, PreQC No. ; Reviewed: 16 September, 2024, QC No. ; Revised: 23 September, 2024, Manuscript No. ; Published: 30 September, 2024,DOI: 10.37421/2684-4591.2024.8.279.

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Citations: 11

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Journal of Interventional and General Cardiology peer review process verified at publons

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