Journal of Cytology & Histology

The Impact of Immunohistochemistry in Histopathological Diagnosis

Abstract

Janiklas Minky*

Histopathological examination is a fundamental tool in the diagnosis and prognosis of various diseases, including cancer. Traditional histopathology relies on the visual analysis of tissue samples, often accompanied by stains that highlight specific features. However, this method has limitations, especially when distinguishing between different tissue types and subtypes. Immunohistochemistry (IHC) has revolutionized histopathology by introducing the use of antibodies to detect specific proteins within tissues. This article explores the significant impact of immunohistochemistry in histopathological diagnosis, discussing its principles, applications, advantages, and challenges. Immunohistochemistry, histopathological diagnosis, antibodies, tissue samples, cancer, proteins. Histopathological diagnosis plays a crucial role in the assessment and management of various diseases, including cancer. Traditionally, pathologists relied on Hematoxylin and Eosin (H&E) staining to visualize tissue samples, but this method often had limitations, especially when differentiating between various tissue types and subtypes.