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Virology: Current Research

ISSN: 2736-657X

Open Access

The Interplay between Infection and Vasculitis: Insights and Uncertainties

Abstract

Malhar Parihari*

The COVID-19 pandemic has indeed brought to light various uncertainties and complexities regarding the transmission of respiratory pathogens among individuals. Traditionally, it was widely believed that respiratory pathogens primarily spread through large droplets generated during activities like coughing and sneezing, as well as via direct contact with contaminated surfaces, known as fomites. Numerous human studies and animal models have pointed to the involvement of various infectious agents in the development of vasculitis, particularly in susceptible individuals. However, the relationship between infection and vasculitis is exceedingly intricate and not yet fully comprehended. What makes it even more complex is that different agents can trigger the same type of vascularise, as is evident in the case of Leukocytoclastic Vasculitis. Conversely, the same infectious agent can evoke a wide spectrum of host responses.

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