WiesÅaw B and Lasek-Bal A
Metastases to the brain and spinal cord meninges concern 4-15% of patients with solid tumors. The most frequently occur intracranial in the course of hematological malignancies, lung and breast cancers and predict poor prognosis. Leptomeningeal metastases (LM) are usually a late complication of malignancy occurring from six months to three years after diagnosis of primary tumor. The median survival time of patients with dissemination into meninges is approximately two months; that period is the longest in the patients with breast cancer (79 days).
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