Journal of Clinical Case Reports

The relationship between established Immunity and the type of Covid-19 Vaccine

Abstract

Kimia Ghods

Statement of problem: Corona virus epidemic which started in 2019, has caused a widespread disaster around the world. Many efforts have been to develop safe and effective vaccines to prevent Covid-19 disease, and eventually a number of vaccines with different platforms have been licensed for use in various countries. Numerous studies have shown that these different structures of Covid 19 vaccines each uniquely activate and strengthen the host immune system, and therefore the immunity obtained from each vaccine is different. In this article, we will discuss the difference between the structures of Covid 19 vac cines and its effect on immunity obtained. Methodology & Theoretical Orientation: An electronic search applying specific Mesh terms like Covid 19, Vaccines, Immunity was carried out in PubMed and Google Scholar databases to collect data from 2020 until 2021, considering basic, pre-clinical, clinical and review studies. 42 relevant articles, focused on "Covid-19 vaccines and immunity" were selected and explored. Findings: According to the latest studies, all the Covid-19 vaccines platform will establish an acceptable immunity in the host. However, it has been shown that vaccines containing killed or inactivated virus produce lower immune responses than vaccines containing live virus and require booster doses. Conclusion & Significance: Undoubtably, all different types of Covid-19 vaccines can exclusively establish a good host immunity response. Therefore, the best solution to overcome this pandemic is to accelerate global vaccination and trust the outcome.