Journal of Spine

The Role of Chondrocytes in Fracture Healing

Abstract

Fan Jin, Yin Jian, Chen Jian and Fang Jiahu

Inflammation plays important roles in the early steps of fracture healing including, the recruitment, expansion, growth and differentiation of mesenchymal stem cells (MSCs), the coordinated interplay of many other cell types, growth factors, and extracellular matrix (ECM) components, as well as the production of cartilage and bone matrix in a temporally controlled manner.