Tissue integration, also known as osseointegration, is a crucial process in the field of biomaterials and tissue engineering. It involves the establishment of a functional and structural connection between an implanted biomaterial and the surrounding host tissues. Successful tissue integration is essential for the long-term stability and functionality of various biomedical applications, including orthopedic and dental implants, as well as tissue-engineered constructs. This article provides an in-depth exploration of tissue integration, discussing its significance, underlying mechanisms, factors influencing integration, and recent advancements in the field. Additionally, it highlights future perspectives and challenges, such as personalized medicine, immunomodulation, smart implants, and the integration of biological and synthetic materials, which will shape the future of tissue integration research.
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Journal of Tissue Science and Engineering received 807 citations as per Google Scholar report
