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Journal of Inflammatory Bowel Diseases & Disorders

ISSN: 2476-1958

Open Access

Tumor Necrosis Factor-alpha: Implications for Tissue Damage in Chronic Inflammation

Abstract

Mankarious Greene

Tumor Necrosis Factor-alpha (TNF-α) is a pro-inflammatory cytokine that
plays a pivotal role in regulating immune responses and inflammation in the
body. Originally identified for its ability to induce tumor cell death, TNF-α is
now recognized as a critical mediator in a variety of inflammatory conditions,
both acute and chronic. While TNF-α is essential for mounting an effective
immune response to infection or injury, its overproduction or dysregulation
is associated with a wide array of chronic inflammatory diseases, including
rheumatoid arthritis, Inflammatory Bowel Disease (IBD), psoriasis, and even
Chronic Obstructive Pulmonary Disease (COPD).

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Citations: 77

Journal of Inflammatory Bowel Diseases & Disorders received 77 citations as per Google Scholar report

Journal of Inflammatory Bowel Diseases & Disorders peer review process verified at publons

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