Jumina Relio*
Polygenic traits are characteristics influenced by multiple genes, often exhibiting complex inheritance patterns. This review explores the mechanisms underlying polygenic traits, their genetic architecture, methodologies for studying them, and the implications for health and disease. By synthesizing current research, we aim to provide a comprehensive understanding of how polygenic traits contribute to phenotypic variation and the challenges involved in their analysis. Polygenic traits, such as height, skin color, and susceptibility to diseases like diabetes and heart disease, are shaped by the interplay of numerous genetic factors. Unlike Mendelian traits, which are influenced by single genes, polygenic traits involve the cumulative effect of variations across many loci. This complexity poses significant challenges in genetic research, making the unraveling of polygenic traits a crucial endeavor in the fields of genetics, genomics, and medicine.
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Human Genetics & Embryology received 309 citations as per Google Scholar report
