Journal of Clinical Case Reports

Unusual Case of Post-Infection Nephritis Associated with Nephrin Mutation

Abstract

Osamay Safdar, Badr Alaifan, Abdulillah Turkistany, Ghadeer Mokhtar and Sherif Aldesoky

NPHS1 gene is the gene responsible for production of Nephrin, which has role in the structure of glomerular filtration barrier. Nephrin located in slit diaphragm, which has a role in preventing passage of plasma proteins out of glomerular capillaries.