Cardiovascular Diseases & Diagnosis

Unusual Life-Threatening Protamine Reaction in a Patient after off Pump CABG - A Case Report

Abstract

Sujit Kumar Mohanty, Farooqi A, Satpathy SK, Rama Krishna G, Trivedi J, Mahapatra RK, Ravi and Nooruddin

Immunologic reactions to protamine sulphate during cardiac surgery are very rare. The frequency and outcome of such adverse reaction is unclear. Clotting of distal anastomosis sites and proximal site (in aorta) is very rare. We report a case of unusual life-threatening reaction to protamine that occurred in a non-diabetic patient following the uneventful off pump coronary artery bypass grafting operation.