The use of Extracellular Vesicles (EVs) has emerged as a promising approach in the diagnosis and treatment of chronic liver conditions. Chronic liver diseases, including cirrhosis, Non-Alcoholic Fatty Liver Disease (NAFLD) and viral hepatitis, present significant health challenges worldwide. EVs, such as exosomes and microvesicles, are membrane-bound particles released by various cell types, carrying a cargo of proteins, nucleic acids and lipids. This review explores the diagnostic and therapeutic potential of EVs in the context of chronic liver diseases. By highlighting the role of EVs in liver disease pathogenesis, biomarker discovery and their application in drug delivery, this review underscores the significant advancements and future possibilities of EV-based strategies in managing and understanding chronic liver conditions.
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