Journal of Biodiversity & Endangered Species

Utilizing Supercritical Carbon dioxide in Biologically Extracted Chitin Hydrogels to Scaffold Human Osteoblasts

Abstract

Zacualpan Ellenberg*

Utilizing supercritical carbon dioxide (scCO₂) in biologically extracted chitin hydrogels presents a promising approach for scaffolding human osteoblasts. Chitin, a biopolymer derived from crustacean shells, is widely recognized for its biocompatibility and potential in tissue engineering. In this article, we explore the utilization of scCO₂ as a green solvent to fabricate chitin hydrogels, focusing on its effectiveness as a scaffold for promoting osteoblast growth and differentiation. We discuss the advantages of scCO₂ processing, including its mild conditions, ability to maintain biomolecule integrity and environmentally friendly profile. Moreover, we review the current research and applications of chitin hydrogels in osteoblast scaffolding, highlighting their role in enhancing bone regeneration and repair. This review underscores the potential of scCO₂-treated chitin hydrogels as advanced biomaterials for orthopedic applications, offering insights into future directions and challenges in this burgeoning field.