A group of alterations known as involve the addition or deletion of a large or small portion of genetic material. Copy number variation has been found and profiling studies on chromosomes have reported amplification. Anaplastic lymphoma kinase gene amplification on chromosome patients was found in previous copy number studies changes in specimens collected prior to systemic therapy were evaluated and compared in this observational study to those in non- patients. In comparison to patients, we observed a statistically significant loss on chromosome patients showed the suggested gain on chromosome, data not shown receptor status, we found a novel enrichment for gain on chromosomes after adjusting for multiple tests, gain near the gene produced the strongest signal changes were also found in patients in comparison Breast cancer has been linked to higher protein levels.
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