Full Text Content : List of Headings Add Content

Article Name - Recent Advances in HIV-1 Integrase Strand Transfer Inhibitors Synthesis Including Pyridine Moiety

Heading Content Date Edit Delete
  • Introduction HIV-1 Integrase Strand Transfer Inhibitors (INSTIs) have revolutionized the treatment of HIV infection by targeting the integration step of the viral replication cycle. Recent developments in ... 2023-09-05
  • Description HIV-1 integrase plays a crucial role in the viral replication cycle by catalysing the integration of viral DNA into the host genome. INSTIs are a class of antiretroviral drugs that target the ... 2023-09-05
  • Conclusion In conclusion, the synthesis of pyridine-based HIV-1 INSTIs represents an active area of research, driven by the need for more potent and effective antiretroviral agents. Recent advances in th ... 2023-09-05
  • Acknowledgement None. ... 2023-09-05
  • Conflict of Interest None. ... 2023-09-05
  • References Cooper, David A., Roy T. Steigbigel, Jose M. Gatell and Jurgen K. Rockstroh, et al. "Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection." N Engl J Med 359 (2 ... 2023-09-05