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Article Name - Chemotherapy-resistant TNBC: Molecular Mechanisms, Biomarkers and Emerging Therapies

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  • Introduction Chemotherapy-resistant Triple-Negative Breast Cancer (TNBC) represents a significant challenge in oncology. TNBC is characterized by the absence of Estrogen Receptors (ER), Progesterone Recept ... 2024-07-12
  • Description The DNA Damage Response (DDR) pathway is also implicated in chemotherapy resistance. Defects in DDR, particularly in the homologous recombination repair (HRR) pathway, can lead to genomic inst ... 2024-07-12
  • Conclusion Clinical trials remain essential for advancing the treatment of chemotherapy-resistant TNBC. Participation in clinical trials provides patients with access to innovative therapies and contribu ... 2024-07-12
  • Acknowledgement None. ... 2024-07-12
  • Conflict of Interest None. ... 2024-07-12
  • References Longley, D. B. and P. G. Johnston. "Molecular mechanisms of drug resistance." J Pathol: J Pathol Soc Great Britain and Ireland205 (2005): 275-292. Google Scholar, Crossref, Index ... 2024-07-12