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Article Name - Research on Pyrazole Derivatives via Molecular Modeling to Create Robust Rearranged during Transfection Kinase Inhibitors

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  • Introduction Pyrazole derivatives have garnered significant attention in the realm of medicinal chemistry due to their versatile pharmacological activities. Among these, their potential as kinase inhibitor ... 2024-07-12
  • Description To further refine the inhibitors, Molecular Dynamics (MD) simulations are conducted. MD simulations provide a dynamic picture of the binding interactions over time, accounting for the flexibil ... 2024-07-12
  • Conclusion The research on pyrazole derivatives via molecular modeling to create robust RET kinase inhibitors highlights the synergy between synthetic chemistry and computational techniques in drug disco ... 2024-07-12
  • Acknowledgement None. ... 2024-07-12
  • Conflict of Interest None. ... 2024-07-12
  • References Roskoski Jr, Robert and Abdollah Sadeghi-Nejad. "Role of RET protein-tyrosine kinase inhibitors in the treatment RET-driven thyroid and lung cancers."Pharmacol Res128 (2018): 1-17. ... 2024-07-12