Diabetic amyotrophy, also known as diabetic lumbosacral radiculoplexus neuropathy, is a debilitating and relatively rare complication of diabetes mellitus. It is characterized by the sudden onset of severe pain, weakness and atrophy in the muscles of the lower extremities. While not as well-known as other diabetesrelated complications, such as neuropathy or retinopathy, understanding and recognizing diabetic amyotrophy is crucial for timely diagnosis and effective management. This article aims to shed light on the causes, symptoms, diagnosis and treatment options for diabetic amyotrophy.