Clinical studies on L-carnation and type 2 diabetes
Several clinical studies have investigated the potential of L-carnitine in the treatment of type 2 diabetes. A randomized controlled trial involving 60 patients with type 2 diabetes found that L-carnitine supplementation improved insulin sensitivity and reduced oxidative stress markers [3]. Another study involving 60 patients with type 2 diabetes found that L-carnitine supplementation reduced fasting blood glucose levels and improved lipid profiles [4]. A meta-analysis of 9 randomized controlled trials found that L-carnitine supplementation significantly improved glycemic control and lipid profiles in patients with type 2 diabetes [5].
Mechanisms of action
The mechanisms of action of L-carnitine in the treatment of type 2 diabetes are not fully understood. However, it is believed that L-carnitine may improve insulin sensitivity and glucose uptake by enhancing mitochondrial function and reducing oxidative stress. L-carnitine may also improve lipid metabolism and reduce inflammation, which are both implicated in the development of insulin resistance and type 2 diabetes.