Gelb Y1*, Castaneda S2, Castaneda L2, and Allison-Aipa T3
Objective: Depression, Post-Traumatic Stress Disorder (PTSD) and anxiety are on the rise in America. The current study was the first of its kind,
highlighting the effects of the Emotion Code, and contributed to the research on alternative healing.
Materials and Methods: This research evaluated whether the EC healing modality had a significant impact on a population of 146 participants.
Individuals completed pre- and post-treatment assessments measuring depression, anxiety and PTSD symptomatology, as well as sociodemographic
characteristics. The measures utilized were self-report questionnaires including: the PTSD Checklist for DSM-5 (PCL-5), Zung Anxiety Scale, and
Patient Health Questionnaire-9 (PHQ-9); they were administered pre-treatment and post-treatment and the scores were compared. The treatment
administered is called The Emotion Code, which is a modality that utilizes manual muscle testing and energy healing to access the subconscious
mind that locates trapped emotions in the body and releases them with the use of intention.
Results: Results show significant decreases in symptomatology in all three mental health categories. These results suggest that the EC healing
method may be a useful tool in aiding to decrease reported symptoms in the areas of anxiety, PTSD, and depression.
Conclusion: This was the first study of its kind, and future studies should be conducted to replicate the results, and compare a treatment group
with a comparable control group.
Vidan D and Oliver F
Within the Swiss research project "Hanno" (derived from an old strategy in Japanese sword fighting) the process of self-healing induced by Gyoki touch is experimentally analyzed. For this purpose, different state-of-the-art measurement technologies are evaluated in order to enable the observation of the effects caused by Gyoki touch and to deterministically document their modes of action. So far, two studies have been published using infrared screening on the one hand and Heart Rate Variability (HRV) monitoring on the other hand; both methods are suitable for measuring Gyoki induced self-healing processes and enable insights into the effects and functioning principles of Gyoki touch.
Roni Sharon
Primary headache and Migraine are common conditions in every society and are the 6th leading cause of disability worldwide, affecting approximately 12% of Americans and millions worldwide, resulting in an inability to attend work or school for at least 1 day every 3 months. Numerous pharmacological options exist for headaches treatment, but these therapies come at high cost and carry numerous potential adverse effects. Yoga is an ancient Indian non-religious technique that is known to aid in treatments of chronic conditions such as stress, anxiety, depression, hypertension and diabetes, and have a substantial effect on reducing headache burden. Research studies have been conducted to demonstrate the effectiveness of yoga lifestyle modifications and exercise on chronic pain syndromes, specifically in primary headache and migraine. Yoga was shown to improves quality of life, reduce headache intensity and headache frequency, when used alone or as an adjuvant to conventional therapy and show a significant decrease in headache frequency and intensity along with a reduction in the use of symptomatic medication. Yoga, being a slow non-exertional aerobic exercise, enhances mood and alleviates stress and depression in adults and invaluable treatment alternative in the pediatric population, where it can create a sustainable healthy lifestyle.
Rishu Sharma and Gyanendra Datta Shukla
Sujithra TS, Mangayarkarasi N, Manavalan N, and Prabu P
Yan W, Weng J, Chang DM, and He M
Objective: The COVID-19 pandemic is the largest public health crisis of this century. Challenges include the overactive immune responses such as cytokine storm and hyper-inflammation, increased likelihood of severe complications in high-risk populations, limited treatment options mainly based on supportive care and potential long-term complications from clinical management. Falun Gong was the most popular qigong in China before 1999. Limited studies have demonstrated significant positive effects of Falun Gong practice on Health Related Quality Of Life (HRQOL), cellular function and gene expression. A health survey using SF36 in Taiwan revealed significantly higher HRQOL and abstinence of unhealthy behavior including smoking among Falun Gong followers. The health benefits were also observed in those 60 years and older, and those with previous chronic conditions, all of which are among the high-risk populations in COVID-19 for severe complications. Gene expression and cellular study results of Falun Gong practice were characterized by enhanced immunity, down regulation of cellular metabolism, and alteration of apoptotic genes in favor of a rapid resolution of inflammation. Biophysical and bio-energy study demonstrated enhanced energy field and cellular function. We hypothesized that the practice could play a potentially significant role in supporting the prevention, treatment and reducing long-term complications of COVID-19. Methods and Results: By searching the internet using diagnosis as keywords, including “SARS”, “Novel Coronavirus Pneumonia”, “Pulmonary Fibrosis”, and “Femoral Head Necrosis”, we found different number of cases in which patients recovered by learning and practicing Falun Gong. Conclusion: These results suggest potential benefits of Falun Gong practice in the prevention, treatment and prognosis in COVID-19 and warrant further studies.
Diksha, Gaurav Badoni, and Manju O. Pai
Introduction: For centuries medicinal plants serve as a curative agent for many respiratory viruses. The emergence of another respiratory virus i.e. SARS-CoV-2 has already affected many lives worldwide. The unavailability of antivirals drugs and vaccines against COVID-19 has drawn attention to alternative therapy. This review article focused on the antiviral activity of medicinal plants as an alternative therapy to combat COVID-19. Materials and Methods: Literature search was performed using scientific web portals including PubMed, Google Scholar, Scopus, and Science Direct. This covered articles published in English language from 1953-2020 for antiviral activity of medicinal plants against respiratory viruses. Data from Clinical Trials Registry- India was used to assess the current herbal trials used for the treatment of COVID-19. Results: Studies showed that medicinal plants significantly inhibit the pathogenesis of respiratory viruses by acting as an immune booster, inhibiting viral attachment, entry, and replication into the host cell. Some of the proven ones for their antiviral efficiency are Ashwagandha (Withania sominifera), Tulsi (Ocimum sanctum), and Giloy (Tinospora cardifolia). Conclusion: From the above finding, it can be anticipated that these medicinal plants may provide antiviral compounds in the future and can be used as an alternative therapy against COVID-19.
DOI: 10.37421/2427-5162.2024.13.523
Novel COVID-19 pandemic is shifting the outlook of the world on every materialistic thing. After each departing day, there are some points for optimism and agony both. Researchers are doing their best to slow down this contagious disease. Slowly the recovery rate is also boosting up. Now a new challenge is approaching up as post-recovery phase symptoms or follows up symptoms. Among the recovered individuals the mental symptoms like depression or stress are the most striking ones. The different modalities available for inner peace or reducing the depression, the meditation is most reliable and through different studies done on various parameters most evidence-based also. The practice of meditation in post recovered persons will not only bring inner solace reducing the physiological symptoms but will also reduce spending on health.
Davood Ershadi*, Mahmood Ashrafi, Mehrdad Memarzade and Ziba Farajzadegan
DOI: 10.37421/2327-5162.2024.13.522
Neuroblastoma is more frequent extra cranial childhood malignancy the goal of this study is evaluate pattern of neuroblastoma and 2 years survival in isfahan and comparison with others studies. The counted cases were 45 patients.25 of them were male (55.6%) and 20 of them were female (44.4%). Female/male ratio was 1.25. Primary sites of tumor in 32 patients were retroperitoan (71%), in 8 patients were posterior mediastineum 17.8%, in 3 patients were cervical 6.7% in pelvis 4.4%. In clinical manifestation the abdominal mass is predominant (17 patients 37.8%), abdominal pain in 6 patients 13.3%, abdominal distention in 2 patients (4.4%) fever in 6 patients (13.3%), cervical mass in 4 patients (6.7%), weight loss in 1 patient (2.2%). In evaluation of bone marrow biopsy 22 patient have metastasis to bone (48.8%) and 23 patients have not metastasis (51.1%). In evaluation of peripheral blood smear 29 patient have hypochrome RBC (64.4%) 32 patients have anisocytosis (71.1%), 30 patients have microcytosis (66.7%), 7 patients have low platelets (15.6%), 6 patients have high platelets 13.3%, 5 patients have lymphocytosis (11.1%), 7 patients have atypical lymphocyte (15.6%) 35 cases of them had died (77.8%), and 10 patients had been being alive (22.2%). Statistical analysis show us mean survival of patient with surgical process was 38.8 months and for patient without surgery was 30.6 months. Total 30 month survival in our study was 50%. Female/male ratio (1.25) in our study is same as other studies like a study in Saudi Arabia 53% of our cases was under 20 months 0.44% of them between 20-80 months 3% over 10 years as same result of others study. Retroperitoan is dominant primary site (71%) like other studies. But there is not significant relation between metstatic bone marrow biopsy and survival. Our result about prognosis (30 month survival was 50%) is less than other countries.
Mehdi Mohammadi Kanesbi*, Lida Jarahi, Hossein Ayatollahi and Maryam Sheikhi
DOI: 10.37421/2327-5162.2024.13.523
Background: Acute Promyelocytic Leukemia (APL) is a well-defined subtype of Acute Myelocytic Leukemia (AML) and known by t (15;17) (PML-RARA) mutation. 20%-40% of AML patients indicate FMS-Like Tyrosine kinase 3 (FLT3) mutations. FLT3 mutations contain two famous mutations: FLT3-ITD (Internal Tandem Duplication) and FLT3-TKD (Tyrosine Kinase II Domain).
Objectives: Many studies have been done on FLT3-ITD. These studies have been acknowledged that the FLT3-ITD mutation had poor prognosis of on AML patients. This study was performed on two APL and APL+FLT3-ITD groups. This study aimed to compare differences in blood laboratory assays between APL and APL+FLT3-ITD patients.
Methods: This study contained 73 patients which divided in two groups: Acute promyelocytic leukemia and FLT3-ITD+acute promyelocytic leukemia. The study methods included: Cell counting and Peripheral Blood Smear (PBS), karyotype, extraction of mRNA and DNA, cDNA synthesis electrophoresis.
Results: This study was ruled out on patients involved with acute promyelocytic leukemia in GHAEM hospital Mashhad, Iran. All patients were diagnosed with t (15; 17) (PML-RARA). The age range of patients was 7-63 (mean: 30.86) and 58 (79.5%) (Male: 22, Female: 36) of patients were involved solely with APL and 15 (20.5%) (Male: 10, Female: 5) of them were APL+FLT3-ITD mutation. Blood parameters that were analyzed included: White Blood Cell (WBC), Red Blood Cell (RBC), Hemoglobin (Hb), Hematocrit (Hct), Mean Cell Volume (MCV) and Platelet (PLT) count. Each group of patients’ population was categorized into HIGH Risk factors and LOW Risk factors.
Conclusion: The consequence of current study demonstrated that FLT3-ITD mutation had a bad effect on laboratory assays in patients involved with Acute Promyelocytic Leukemia.
DOI: 10.37421/2327-5162.2024.13.521
Over the past year many studies and clinical trials have been published in the osteoarthritis field. This research is based on how osteoarthritis develop by reporting the pathophysiology, prognosis, diagnosis and its treatments. We can cure osteoarthritis using the homoeopathic law "Similia Similibus Curanter," which aids in the treatment of the disease and by finding out the miasmatic approach.
Anjali Dharmani*, Chandramani Parinit, Sumaiya Patel, Seema Kapadiya, Sahiba Jamil and Apurva Dixit
DOI: 10.37421/2327-5162.2024.13.520
Iron Deficiency Anemia (IDA) is one of the most common dietary deficiencies, accounting for about half of all instances of anemia. It is widespread in many impoverished nations. In most cases, thorough blood analysis and high serum ferritin levels may be used to diagnose this deficient disease. IDA may develop as a result of physiological pressures placed on developing children, adolescents, and pregnant women. In the case of all patients, however, the underlying reason should be explored. Inevitably, proper therapy of this illness improves quality of life, reduces iron deficient symptoms, and reduces the risk of death. The necessity of a blood transfusion oral iron supplementation and intravenous iron therapy are two therapeutic options. As a result, intravenous iron supplementation is regarded an undesirable technique, and the safety problems connected with this strategy in the event of extremely high dosages or in the context of very high ferritin levels are not well understood. The review's goal is to give a critical overview and up to date information about IDA diagnosis and treatment options.
DOI: 10.37421/2427-5162.2024.14.519
SB Singh*, Poornima Mansoria and Savita Sharma
DOI: 10.37421/2427-5162.2024.14.518
The global pandemic of the Corona virus disease (COVID-19) has caused widespread morbidity and mortality globally. The complicated pathophysiology of COVID-19 and lack of a single therapy have made management a significant issue. Through comprehensive pharmacological, toxicological, and clinical research, AYUSH-64, a poly-herbal formulation developed by CCRAS, ministry of AYUSH, government of India, has demonstrated both its safety and effectiveness in treating infective febrile illnesses like malaria and influenza. Four components in AYUSH-64 include antiviral, immunomodulatory, anti-inflammatory, antipyretic, and anti-inflammatory properties. In COVID-19, it stops the inflammatory responses that lead to substantial morbidity. The government of India has also included AYUSH-64 in the National COVID management protocol based on Ayurveda and Yoga for asymptomatic and mild cases of COVID-19. The study summarizes the therapeutic potential of AYUSH-64 on the basis of clinical trials conducted in India on COVID-19.
Mojdeh Pourhosseini, Hossein Moradi, Fatemeh Nojavan and Abolfazl Mohammadbeigi*
DOI: 10.37421/2427-5162.2024.14.517
Introduction: Soo ul qinya/pre dropsy is one of the liver diseases that also named as pre-dropsy. But, yet there is no precise method for diagnosis this disease. Therefore, this study aimed to develop “Soo Ul Qinya/Pre Dropsy” Diagnostic Tool (SUQDT) in traditional Persian medicine.
Materials and methods: A review study was conducted at 2018 on all 906 books and among credible texts of traditional Persian medicine that have been registered on noor islamic software was checked exactly. Moreover, "soo ul qinya" and "su ul qinya" and "pre dropsy" and "Sualaqani "Pish Istiqa" keywords was used for strategic searches in PubMed, Google Scholar, Scopus and Since Direct, web of sciences, SID and Irandoc. Finally, 15 reference books were chosen. The scoring of "soo ul qinya" signs conducted based on the number of repetition of each signs and symptoms and weighted by inverse-variance method.
Results: Of all traditional Persian medicine’s books, 15 title had detailed about "soo ul qinya" disease. Overall, 29 different signs have been pointed in three groups including absolute signs (pallor, edema of feet, hands, face, eyelids), probable but important signs (poor digestion, heavy feeling or fatigue) and probable but less important signs (perspiration decrease, increased appetite). Based on the number of repetitions and sign weight, the final score of each sign will be yielded and the SUQDT developed.
Conclusion: The "soo ul qinya" disease is not a well-defined but a diagnostic tool named SUQDT was developed based on different signs of disease and assessing the psychometric properties of it suggested.
DOI: 10.37421/2427-5162.2024.13.526
DOI: 10.37421/2427-5162.2024.13.525
DOI: 10.37421/2327-5162.2023.12.442
DOI: 10.37421/2327-5162.2023.12.443
Numerous diseases, including cancer, functional illnesses like chronic fatigue syndrome and fibromyalgia, cardiometabolic conditions like coronary artery disease, hypertension, heart failure and diabetes, among others, are preventable in secondary, primary and primordial ways with regular exercise. Regular exercise has also been demonstrated to lower the risk of physical dependency and impairment, as well as mortality from all causes, happiness and lifespan. It is particularly interesting because cardiorespiratory fitness is now regarded as a substantial quantitative predictor of all-cause mortality and may be a more accurate predictor of death than recognised risk variables. Clinically, the biggest documented reduction in mortality is shown when a patient's cardiorespiratory fitness is raised from a low level (ability to complete an activity between six and eight METs) to a moderate level (capacity to perform an exercise between six and eight METs). Lean body mass and lifespan are also shown to be positively correlated, especially in individuals with low body mass index (BMI); low muscle mass was more strongly and substantially connected with all-cause death than was poor muscular strength.
DOI: 10.37421/2327-5162. 2023.12.444
High glycemic foods, on the other hand, are linked to postprandial hyperglycemia and hyperinsulinemia, which can lead to appetite and, eventually, weight gain. Numerous studies have questioned whether sugar is the only cause of diabetes (not particularly addressed in any randomisedcontrolled experiment) or obesity, but the bulk of them have been unable to substantiate even a single association. Most likely, increased energy consumption, which results in overweight, obesity and type 2 diabetes, is the main pathogenic event. These deadly illnesses wouldn't be brought on by consuming one calorie or one teaspoon of sugar every second. In reality, several published research have revealed no association between sugar consumption and body weight when overall caloric intake is taken into consideration.
DOI: 10.37421/ 2327-5162.2023.12.446
DOI: 10.37421/2327-5162.2023.12.445
DOI: 10.37421/2427-5162.2024.13.514
DOI: 10.37421/2427-5162.2024.13.511
DOI: 10.37421/2427-5162.2024.13.507
Objective: To systematically review the impact of Mindfulness-Based Stress Reduction (MBSR) on quality of life (QoL) among cancer patients.
Methods: A comprehensive search was conducted in databases including PubMed, Cochrane Library and PsycINFO for studies published up to July 2024. Inclusion criteria encompassed randomized controlled trials (RCTs) and quasi-experimental studies evaluating MBSR interventions in adult cancer patients, with QoL as a primary or secondary outcome. Data on study characteristics, participant demographics, intervention details and QoL outcomes were extracted. A meta-analysis was performed to determine the overall effect of MBSR on QoL, with subgroup analyses based on cancer type, stage and MBSR duration.
Results: A total of 20 studies involving 1,200 participants were included. The meta-analysis indicated a moderate effect size for MBSR in improving QoL (Standardized Mean Difference [SMD] = 0.45, 95% Confidence Interval [CI] [0.35, 0.55]). Subgroup analyses showed that MBSR was particularly effective for patients with breast cancer (SMD = 0.50, 95% CI [0.38, 0.62]) and those in the early stages of treatment (SMD = 0.48, 95% CI [0.36, 0.60]). Variability in intervention protocols and outcome measures were noted.
Conclusion: MBSR demonstrates a moderate improvement in QoL for cancer patients, with notable benefits observed in specific cancer types and treatment stages. The findings support the integration of MBSR into cancer care, though further research is needed to optimize program delivery and assess long-term effects.
DOI: 10.37421/2427-5162.2024.13.508
Type 2 diabetes (T2D) represents a significant global health challenge, characterized by insulin resistance and high blood glucose levels. While conventional treatments primarily involve lifestyle modifications and pharmacotherapy, there is increasing interest in integrative approaches that combine traditional and complementary therapies. This article reviews the efficacy of integrating conventional treatments with complementary therapies such as dietary supplements, acupuncture and mind-body practices, exploring their potential benefits and limitations in managing T2D.
DOI: 10.37421/2427-5162.2024.13.509
Anxiety and depression are prevalent mental health conditions that significantly impact quality of life and overall well-being. Conventional treatments, including psychotherapy and pharmacotherapy, are commonly used to manage these disorders. Recently, yoga therapy has emerged as a complementary approach with potential benefits for mental health. This study aims to compare the effects of yoga therapy with conventional treatments on anxiety and depression, evaluating their efficacy, mechanisms and practical implications.
DOI: 10.37421/2427-5162.2024.13.510
Traditional Chinese Medicine (TCM) has been used for centuries in China and other parts of Asia for the prevention and treatment of various diseases, including cancer. Recently, interest in TCM has grown in the Western world as a complementary approach in oncology. This review aims to synthesize the current evidence from clinical trials on the efficacy and safety of TCM in cancer treatment, focusing on outcomes such as symptom management, quality of life and survival rates. The review also discusses the integration of TCM with conventional cancer therapies and identifies future research directions.
DOI: 10.37421/2427-5162.2024.13.512
DOI: 10.37421/2427-5162.2024.13.513
DOI: 10.37421/2427-5162.2024.13.515
DOI: 10.37421/2427-5162.2024.13.516
Alternative & Integrative Medicine received 476 citations as per Google Scholar report