Bioceramics Development and Applications

Biomineralization in teeth is a complex and highly regulated process that results in the formation of enamel and dentin, two vital components of the tooth structure. Understanding the mechanisms underlying enamel and dentin formation is crucial for developing strategies to prevent dental diseases such as caries and to promote effective dental treatments. This article reviews the molecular processes, cellular interactions, and key proteins involved in biomineralization within the tooth, highlighting recent advancements and unresolved questions in this field. Insights gained from studying biomineralization in teeth not only shed light on the natural synthesis of mineralized tissues but also inspire biomimetic approaches for dental restoration and regeneration.

Osseointegration is a pivotal process in biomedical engineering, facilitating the seamless integration of artificial implants with natural bone tissue. This article explores the biological mechanisms underlying osseointegration, from initial implant placement to the maturation of bone tissue around the implant. Key factors influencing osseointegration outcomes, including implant materials, surface modifications, and surgical techniques, are examined in depth. The clinical significance of osseointegration in orthopedic and dental applications is highlighted, emphasizing its role in improving patient outcomes and enhancing implant longevity. Current research trends and future directions in osseointegration are also discussed, aiming to further advance implant technology and biological integration.

Bioinert materials are essential in biomedical applications due to their non-reactive nature and compatibility with biological systems. This minireview provides an overview of bioinert materials, focusing on their properties, applications in various medical fields, surface modifications, challenges, recent advances, and future directions.

Soft tissue injuries and degenerative conditions present significant challenges in clinical practice, necessitating effective regenerative strategies to restore tissue structure and function. Bioceramics, traditionally recognized for their applications in bone regeneration, have garnered increasing interest for their potential in soft tissue repair. This article reviews recent advancements, challenges and future directions in the use of bioceramics for soft tissue repair, encompassing different types of bioceramics, their unique properties and applications in various soft tissue contexts, biocompatibility considerations, clinical implications and emerging trends. Understanding the role of bioceramics in soft tissue repair is crucial for advancing regenerative medicine and improving patient outcomes.