Clinical Gastroenterology Journal

Pancreatic cancer presents significant diagnostic and therapeutic challenges, often diagnosed at advanced stages with limited treatment options and poor prognosis. Endoscopic Ultrasound (EUS) has emerged as a pivotal technology in the comprehensive management of pancreatic cancer, offering unparalleled capabilities in early detection, precise staging, and targeted therapeutic interventions. This abstract reviews the evolving role of EUS in pancreatic cancer care, emphasizing its diagnostic accuracy through high-resolution imaging and EUS-guided tissue sampling techniques like Fine-Needle Aspiration (FNA). EUS facilitates accurate staging by assessing tumor extent, vascular involvement, and lymph node status, crucial for treatment planning and determining surgical resectability. Moreover, EUS-guided therapies, including Fine-Needle Injection (FNI) and Celiac Plexus Neurolysis (CPN), provide minimally invasive options for localized treatment and palliative care, respectively. Technological advancements in EUS, such as contrast-enhanced imaging and elastography, continue to enhance diagnostic precision and therapeutic efficacy.

Trigeminal schwannomas are rare, benign tumors that arise from the schwann cells of the trigeminal nerve. Their location in the skull base presents significant surgical challenges due to the intricate anatomy and the proximity to critical neurovascular structures. Traditional approaches to their resection have included the subtemporal, retrosigmoid, and transpetrosal routes. However, the transorbital approach, an emerging minimally invasive technique, offers potential advantages in terms of reduced morbidity and improved cosmetic outcomes. This review systematically examines the literature on the efficacy and safety of the transorbital approach for trigeminal schwannoma resection.

Mesiodens, a type of supernumerary tooth, typically occurs between the central incisors in the oral cavity. Its presence in the nasal cavity is an exceptionally rare anomaly, leading to symptoms such as nasal obstruction, recurrent infections, and epistaxis. Traditional surgical methods for removal can be invasive and complex.

Endoscopic spine surgery has emerged as a transformative approach in spinal interventions, offering minimally invasive alternatives to traditional open procedures. This research article reviews the evolution, current trends, and recent developments in endoscopic spine surgery, highlighting technological advancements, clinical outcomes, and future directions in the field.