Journal of AIDS & Clinical Research

The HIV/AIDS epidemic is a global health crisis that affects diverse populations worldwide. In this article, we focus on the specific context of Minnesota, where a significant population of refugees has been affected by HIV/AIDS from 2000 to 2007. We explore the challenges and unique factors influencing the spread and management of HIV/AIDS in this community, examining both medical and social aspects. The analysis draws attention to the need for culturally sensitive healthcare, education, and support programs to address the distinct needs of Minnesota's HIV-infected refugee population.

In 2015, a cross-sectional study was conducted in Zhejiang, China, to investigate the prevalence of active syphilis infection among HIV-positive men who have sex with men and to identify the associated risk factors. This study sheds light on the intersecting challenges faced by individuals in this vulnerable population and provides valuable insights into the dynamics of Sexually Transmitted Infections (STIs) within the context of HIV in the region. The HIV epidemic in China has been on the rise, particularly among MSM. Simultaneously, the prevalence of syphilis, a bacterial STI, has also been increasing in various parts of the country. Understanding the prevalence and risk factors associated with active syphilis infection in HIV-positive MSM is critical for public health efforts aimed at prevention, diagnosis and treatment.

HIV/AIDS remains a global public health challenge, with millions of people worldwide living with the virus. Effective Antiretroviral Therapy (ART) has transformed HIV into a manageable chronic condition, enhancing the quality of life and extending the lifespan of those affected. However, the emergence of drug resistance mutations in the HIV-1 virus poses a significant threat to the success of ART. This article delves into a study conducted in Russia's Northwestern Federal District, focusing on the prevalence and implications of HIV-1 drug resistance mutations among patients experiencing treatment failure. Russia has been grappling with an expanding HIV epidemic for several years. The country has the highest number of new HIV infections in Eastern Europe and Central Asia, with the Northwestern Federal District being one of the regions most severely affected.

HIV-1 infection remains a global health challenge, with approximately 38 million people living with the virus worldwide. While the advent of highly active Antiretroviral Therapy (HAART) has significantly improved the prognosis and quality of life for individuals living with HIV-1, a complete cure remains elusive due to the persistence of latent HIV-1 reservoirs. HIV-1 latency refers to the ability of the virus to remain dormant in certain cells, evading immune surveillance and antiretroviral drugs. This latent reservoir poses a major barrier to achieving a functional cure for HIV-1. In this review, we delve into the molecular mechanisms underlying HIV-1 latency and discuss current therapeutic approaches aimed at eradicating or controlling this persistent reservoir.