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Journal of Bioanalysis & Biomedicine

ISSN: 1948-593X

Open Access

Volume 15, Issue 4 (2023)

Mini Review Pages: 1 - 2

Advances in High−throughput Proteomic Profiling for Disease Biomarker Discover

Janosch Kraft*

DOI: 10.37421/1948-593X.2023.15.389

High-throughput proteomic profiling has become a pivotal tool in identifying potential biomarkers for various diseases. This article reviews recent advancements in proteomic technologies and their application in biomarker discovery. We discuss the challenges associated with data analysis and integration and explore strategies to enhance the sensitivity and specificity of biomarker identification. By harnessing the power of mass spectrometry, machine learning, and bioinformatics, researchers are making significant strides towards revolutionizing disease diagnosis and personalized treatment strategies.

Mini Review Pages: 1 - 2

Exploring Gut Microbiota−mediated Metabolism of Pharmaceuticals for Personalized Drug Responses

Tarek Porro*

DOI: 10.37421/1948-593X.2023.15.394

The human gut microbiota plays a pivotal role in drug metabolism, impacting drug efficacy and safety. This article delves into the burgeoning field of gut microbiota-mediated drug metabolism and its implications for personalized medicine. We explore the mechanisms underlying microbiotamediated transformations of pharmaceuticals, their influence on drug bioavailability, and their potential to modulate individual drug responses. By elucidating the interplay between gut microbes and drugs, we uncover new avenues for tailoring drug therapies to individual patients, ultimately enhancing treatment outcomes.

Mini Review Pages: 1 - 2

Quantitative Imaging Flow Cytometry: Unraveling Heterogeneity in Single−cell Analysis

Ali Tafaghodi*

DOI: 10.37421/1948-593X.2023.15.396

The study of single-cell heterogeneity is a fundamental aspect of understanding complex biological systems. This article explores the transformative capabilities of quantitative Imaging Flow Cytometry (qIFC) in unraveling the intricacies of single-cell analysis. We discuss the principles, instrumentation, and data analysis techniques associated with qIFC, emphasizing its capacity to provide quantitative and spatial information at the single-cell level. This technology enables comprehensive investigations into cell populations, revealing hidden phenotypic diversity, dynamic responses, and subcellular features. The integration of qIFC is poised to advance our knowledge of cellular biology, immunology, and disease mechanisms.

Mini Review Pages: 1 - 2

Targeted Nanoparticle Delivery of CRISPR−Cas9 System for Precision Genome Editing In vivo

Margherita Fogliano*

DOI: 10.37421/1948-593X.2023.15.397

Precision genome editing holds immense promise for the treatment of genetic disorders, but efficient in vivo delivery of CRISPR-Cas9 components remains a formidable challenge. This article explores the development and application of targeted nanoparticles as a delivery platform for the CRISPR-Cas9 system. We discuss the design, optimization, and in vivo testing of nanoparticles tailored to specific cell types and tissues. The integration of nanotechnology and genome editing not only enhances the precision and efficiency of genome modifications but also paves the way for potential therapeutic breakthroughs.

Google Scholar citation report
Citations: 3099

Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report

Journal of Bioanalysis & Biomedicine peer review process verified at publons

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