Journal of Bioengineering & Biomedical Science

Apoptosis is commonly referred to as programmed cell death that does not cause inflammation. Numerous studies have focused on the intricate nature of apoptosis, accumulating a wealth of information that has led to effective disease treatments as well as a deeper comprehension of the fundamental process. The traditional apoptosis regulatory factors and intrinsic and extrinsic signaling pathways have been clearly defined. Since ancient times, apoptosis-based drugs and treatments have been used to treat disease. In clinical settings, small-molecule apoptosis inducers have been used to treat diseases like cancer by killing off abnormal cells. Recombinant proteins and antibodies, which have improved apoptotic efficacy and selectivity, are the subject of extensive research and the FDA has granted approval to some of them. Apoptotic bodies (ApoBDs) are membrane-bound vesicles that are derived from the disassembly of apoptotic cells. Prior to being discovered to be capable of delivering useful materials to healthy recipient cells (such as autoantigens), these tiny sealed sacs containing information and substances from dying cells were regarded as garbage bags. With a focus on apoptosis-related therapeutic applications and ApoBDs, this review summarizes and discusses current knowledge of apoptosis.

It is essential for patients to bring their medication and other healthcare items with them when they leave their homes during an evacuation because medication loss is a major issue in disaster settings. This article is based on a systematic review of the literature on medication loss. The goal of this review was to find out how much medication is lost, what it means, how much work it takes to get prescriptions filled and how to be better prepared. The review revealed that the medical relief teams are significantly burdened by the loss of medications, prescriptions and medical aids. Drugs are not the only medical aids; routine medications, medical and allergy records, devices for specific care and daily life and emergency medications are also included. A personal emergency pack that people can carry with them at all times is one possible solution. Stakeholders, particularly health professionals, need to be actively involved in the preparation plans in order to guarantee that patients are adequately prepared. We are now taking actions to spread our findings, such as presenting at conferences and through posters, in order to raise awareness among patients and healthcare professionals because our findings have little impact on disaster risk reduction unless shared widely. Our findings were presented at the Evidence Aid Symposium on September 20, 2014, in Hyderabad, India, as part of these activities.