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Journal of Clinical Case Reports

ISSN: 2165-7920

Open Access

Volume 11, Issue 4 (2021)

Case Report Pages: 1 - 3

Painful Leg Moving Toes Syndrome: A Report of Two Cases and Update of Clinical Manifestation, Pathophysiology and Management

Samih Badarny*, Yazid Badarny, Kamal Hassan and Adnan Zaina

Introduction: Painful Leg and Moving Toes (PLMT) is a rare disorder of unknown etiology. It is characterized by pain and abnormal movement of toes. These symptoms are troublesome to patients but not life-threatening. There is no curative treatment; however, supportive therapy and symptomatic therapy somewhat ameliorate the conditions. Thus, also to avoid extensive or invasive examinations, physicians should be aware this condition.

Case presentation: The first patient had sensory symptoms that began in both legs, and gradually involuntary movements appeared in the toes of one leg, which spread to the other leg. The second had no leg pain, but involuntary movement of the toes was the sole clinical presentation. Diagnosing these conditions as PLMT, we prescribed pregabalin, clonazepam, baclofen, local corticosteroid injections, epidural blocks and warmwater soaks, which led to partial improvement of these symptoms.

Conclusion: PLMT presents in different forms, symptoms usually do not worsen over time and not life-threatening, and thus, in this sense, benign condition. We, presenting these two cases, wish to update the clinical presentation, electrophysiological findings, pathophysiology, associated diseases, treatment and management of PLMT

Case Report Pages: 1 - 3

Surgical Management and Outcome of a Ruptured Aseptic Mycotic Cerebral Aneurysm: A Case Report

Sara M. Zorawski*, Daniel Dubinski, Daniel Cantré, Christian Henker, Andreas Erbersdobler, Florian Gessler, Thomas M. Freiman and Sae-Yeon Won

Background: Mycotic aneurysms are a rare subset of intracranial aneurysms caused by bacterial, viral or fungal sources. Rupture of an intracranial mycotic aneurysm is a life-threatening event untreated with a mortality range up to 80%.

Case description: Here, we report the case of a 21-year-old second year female medical student who suffered from a ruptured mycotic aneurysm of the middle cerebral artery with subarachnoid haemorrhage. After surgical resection of the aneurysm, intensive monitoring and treatment of cerebral vasospasm were performed. Further diagnostics for the focus of infection, including laboratory parameters, transoesophageal echocardiography and otolaryngoscopic diagnostic, showed normal findings without any sign of endocarditis, vasculitis or otolaryngitis. After 3 weeks, the patient was discharged in a very well condition.

Conclusion: Aseptic mycotic aneurysm is a rare subtype with posing significant therapeutic challenge. Surgical resection of those aneurysms might be safe and effective treatment

Case Report Pages: 1 - 5

Conversion Therapy for Advanced Gastric Cancer with Apa-tinib Combined with SOX Regimen: A Report of Two Cases and Literature Review

Jun Zhang, Yan Dai and Zhongliang Ning*

In late state gastric cancer, combination chemotherapy with targeted therapy has been employed, which may control the tumor growth and recurrence. We here report two patients diagnosed with advanced gastric cancer which were treated with SOX regimen combined with apatinib for conversion therapy. After three cycles of this combination treatment, the lymph node metastases and tumor decreased in size, which enabled the surgery (R0 resection), with no recurrence for more than 1 year. We believe that apatinib combined with SOX regimen can increase the possibility of successful surgical resection, and thereby prolonging the progression-free survival of patients with advanced gastric cancer

Case Report Pages: 1 - 2

Right Ovarian Vein Thrombophlebitis Complicated by an Inferior Endocaval Floating Thrombus Revealed by Postpartum Pyrexia: A Case Report

Faidherbe Clement*

The clinical course of our patient highlights an atypical presentation of thromboembolic disease related to pregnancy, a thrombophlebitis of the right ovarian vein with endocaval floating thrombus. The diagnosis remains difficult since it is a rare entity with an atypical presentation but with serious medical consequences.

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Citations: 1345

Journal of Clinical Case Reports received 1345 citations as per Google Scholar report

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