Journal of Coronary Heart Diseases

The rapid advancements in genetic research have begun to reshape the landscape of many medical specialties, with cardiology being no exception. Genetic markers, which are specific sequences of DNA associated with particular traits or diseases, have gained significant attention for their potential to personalize treatment strategies for cardiovascular diseases. Traditionally, cardiology has focused on population-level treatments, relying on risk factors such as age, cholesterol levels, and blood pressure. However, genetic insights now allow for more tailored approaches, helping clinicians to predict, prevent, and manage heart diseases in a more individualized manner

The COVID-19 pandemic has had profound impacts on human health worldwide, with long-term consequences emerging in the form of Long-COVID. While the respiratory effects of the virus were initially the primary focus, an increasing body of research has pointed to cardiovascular complications as one of the most concerning aspects of this condition. Cardiologists, in particular, must understand the complexities surrounding Long-COVID’s impact on the heart and vascular system. Studies have shown that individuals who have recovered

Endothelial dysfunction has emerged as a critical factor in the pathogenesis of cardiovascular disease (CVD), playing a pivotal role in the development of conditions such as atherosclerosis, hypertension, and heart failure. The endothelium, the thin layer of cells that line blood vessels, is essential for maintaining vascular homeostasis. Under healthy conditions, endothelial cells regulate

Microvascular Disease (MVD) is an often-overlooked yet significant contributor to cardiovascular morbidity and mortality. It refers to the dysfunction or damage to the small blood vessels in the heart, including the coronary microvasculature, which plays a crucial role in supplying oxygen and nutrients to the heart muscle. Unlike Coronary Artery Disease (CAD), which affects larger blood vessels, MVD occurs in the tiny, intricate network of capillaries and arterioles. Despite its subtle nature, microvascular disease can lead to serious heart-related complications, including chest pain, heart failure, and poor outcomes following heart