Journal of Cosmetology & Trichology

Acne vulgaris, generally known as acne, is a long-term skin disorder in which dead skin cells and oil from the skin block hair cells. Blackheads or whiteheads, pimples, greasy skin, and scarring are all common symptoms of the condition. It primarily affects skin with a high number of oil glands, which includes the face, upper chest, and back. The ensuing appearance can cause depression, negative self, and, in the worst-case scenario, depression or suicidal thoughts. In 80% of cases, acne susceptibility is primarily inherited. Diet and cigarette smoking appear to play no function in the disease, and neither hygiene nor exposure to sunshine appear to play a role. Androgens, which cause increased sebum production in both sexes, appear to be part of the underlying mechanism. Excessive proliferation of the bacterium Cutibacterium acnes, which is prevalent on the skin, is another common reason.

Background: Hair loss is a not life-threatening dermatological condition with some physical effects but with more severe psychosocial consequences. Nutrition deficiencies have been associated to hair loss, opening the door for food supplement’s use in decreasing hair loss.

Objective: The aim of this study was to investigate the efficacy and safety of a commercially available food supplement (Alline proMEN) containing a patented keratin (Keramax®), venus hair fern extract and a combination of 11 vitamins and two minerals.

Patients/Methods: Men with hair loss were randomized to receive a tablet per day of the active or the placebo product over a 3-months study period. Anagen, telogen and hair density were measured as primary endpoints; while hair mechanical properties, hair structure, hair radiance, clinical analysis and self-assessment were investigated as secondary endpoints.

Results: The mean change of the percentage of telogen hair over 1 month product use was -4.6%; while the mean change over 3 months product use was -13.2%. The hair breakage force and the hair elongation were statistically changed after 3 months of product use by +7.5 and 5.3%; while the hair radiance was improved both at 1 and 3 months. These effects were visible also on the clinical analysis, on the hair structure and by the subjects.

Conclusion: In conclusion, the oral supplementation with Alline proMEN for 3 months was effective in speeding up the resolution of the hair loss in men, in improving the hair physical and mechanical properties and was well-tolerated. The product is then a safe and effective way to address hair loss in men.

Background: Metabolic Syndrome (MS) is a real public health problem in our regions. Its severity requires early detection strategies based on clinical, anthropometric and biological criteria to ensure adequate management of this condition. Hyperuricemia, although not part of these criteria, is frequently associated with MS components. Thus, we have set ourselves the goal of finding a relationship between uric acid and MS. Methodology: We conducted a prospective study on 441 subjects received as part of an annual medical visit. The subjects included in the study benefited from a complete clinical examination and blood tests provided by this annual medical check (including blood sugar, lipid status, uric acid). The biochemical parameters were determined using enzymatic methods adapted to the A15 automaton. The metabolic syndrome has been defined according to the criteria of NCEP-ATP III Results: The prevalences of metabolic syndrome and hyperuricemia were 6.57% and 6.34%, respectively. Hyperuricemia was strongly associated with MS (OR = 3.87, p = 0.007) and some of these components including hypoHDlemia (OR = 5.09), hypertriglyceridemia (OR = 3.05), and abdominal obesity (OR = 2.52) Conclusion: The positive association between hyperuricemia and MS demonstrates the interest of dosing uric acid in subjects at risk