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Molecular Biomarkers & Diagnosis

ISSN: 2155-9929

Open Access

Volume 13, Issue 8 (2022)

Mini Review Pages: 1 - 1

Clinical Performance of Biomarkers in Acute Kidney Injury

Eric Solary*

DOI: 10.37421/2155-9929.2022.13.537

Several biomarkers of acute kidney injury (AKI) have recently been discovered and characterised. These molecules, which can be found in urine or blood, indicate structural damage to the kidney. They are being proposed clinically as adjunct diagnostics to serum creatinine and urinary output to improve the early detection, differential diagnosis and prognostic assessment of AKI. The most obvious requirement for a biomarker is that it reflect the disease's underlying pathophysiology. As a result, a biomarker of AKI should be derived from the injured kidney and reflect a molecular process that is intimately related to tissue injury.

Mini-Review Pages: 1 - 1

Molecular Biomarkers in Idiopathic Pulmonary Fibrosis

Yoshie Hongo*

DOI: 10.37421/2155-9929.2022.13.539

The most lethal form of interstitial pneumonia of unknown cause, idiopathic pulmonary fibrosis (IPF), is associated with a specific radiological and histopathological pattern (the so-called "usual interstitial pneumonia" pattern) and has a median survival estimated to be between 3 and 5 years after diagnosis. However, evidence suggests that IPF has different clinical phenotypes, each of which has a different disease course over time. Individual patients' natural histories of IPF are currently unpredictable, though some genetic factors and circulating biomarkers have been linked to different prognoses. IPF may be asymptomatic in its early stages, resulting in a delayed diagnosis. Pirfenidone and nintedanib have been shown to change the course of the disease by slowing the decline in lung function.

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Citations: 2054

Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report

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