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Neurological Disorders

ISSN: 2329-6895

Open Access

Volume 9, Issue 2 (2021)

Research Article Pages: 1 - 4

Using Immunomagnetic Reduction to Assay Reagent Stability of Biomarkers Associated with Alzheimerâ??s Disease

Huei-Chun Liu, Chin-Yi Lin, Hsin-Hsien Chen, Chaur-Jong Hu, Chaur-Jong Hu, Chaur-Jong Hu, Chia-Shin Ho and Shieh-Yueh Yang*

DOI: 10.37421/2329-6895.2021.9.449

Plasma biomarker assays have become a trend for risk evaluation in Alzheimer’s disease. Several studies have been performed to explore their preclinical performance. However, there are very few studies on the storage stability of the reagents used in these assays. The determination of the storage stability of reagents is important because reagents may be stored for a few months prior to end use. In this work, the stability of the reagents used for assaying plasma amyloid β 1-40 (Aβ1-40), Aβ1-42 and total tau protein (Tau) was assessed using immunomagnetic reduction. Reagents immediately after synthesis and reagents in opened vials were used to assay the concentrations of Aβ1-40, Aβ1-42 and Tau in human plasma samples. The recovery rates of the concentrations of biomarkers at different times after synthesis of open vial were calculated to determine the period of stability of reagents. The results showed that the reagents stored at 2°C-8°C were stable for at least 52 weeks. The reagents in open vials were stable for at least six weeks. These stabilities indicate that the reagents used to assay plasma Aβ1-40, Aβ1-42 and Tau levels are verifiably qualified for clinical use.

2021 Conference Announcement Pages: 1 - 1

Globalize your Research at Stroke 2020, Rome

Uqbah Iqbal*

After the grand success of Stroke 2019, we welcome you afresh for the 9th International Conference on Neurological Disorders and Stroke slated on the dates February 28-29, 2020 in Rome, Italy

2021 Conference Announcement Pages: 1 - 1

34th European Neurology Congress scheduled on June 24-25, 2020 at Zurich, Switzerland

Ivan V. Maksimovich*

Neurology is a division of medicine concerned with disorders of the nervous system. It deals with the diagnosis and treatment of all division of conditions and disorder involving the central and peripheral nervous systems, including their coverings, blood vessels and all effector tissue such as muscle. Neurological system relies heavily on the field of neuroscience, the scientific study of the nervous system. The doctor who specially designed in neurology is known as neurologist. The neurologist experienced to investigate or diagnose and treat a neurological disorder that affects the brain, spinal cord, and nerves. Neurologists do not implement surgery if any patient requires surgery they refer to neurosurgeons.

2021 Conference Announcement Pages: 1 - 1

Clinical pediatrics 2020 scheduled on October 28-29, 2020 at San Francisco, USA

Terence T Lao*

The “Clinical Pediatrics 2020” was scheduled during October 28-29, 2020 at San Francisco; USA has been successfully going to be executed. The conference was initiated with the honorable presence of the Keynote forum.

2021 Conference Announcement Pages: 1 - 1

Heart Brain 2020: A new path towards the new research for neurology and cardiology

Walter Bini*

World Heart and Brain conference is an interesting meeting that joins together cardiologists and neurologists in arrange to seek after all-encompassing approach to understanding the association between the heart and the brain. As a pioneer within the developing multidisciplinary field of neuroradiology, Heart Brain 2019 has set the standard within the quickly developing field of coordinates pharmaceutical that empowers a wide range of information for progressed hone and persistent care. We are organizes a arrangement of conference over 1000+ Worldwide Occasions comprehensive of 300+ Conferences, 500+ Up and coming and Past Symposiums and Workshops in USA, Europe & Asia with bolster from 1000 more logical social orders and distributes 700+ Open get to journals which contains over 30000 famous identities, rumoured researchers as publication board individuals. Worldrenowned speakers, the foremost later strategies, propel, and the most current overhauls in neurology are trademarks of this conference.

Google Scholar citation report
Citations: 1343

Neurological Disorders received 1343 citations as per Google Scholar report

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