Journal of Pediatric Neurology and Medicine

One of the most common causes of disability worldwide, bipolar disorder (BD) affects more than 1 percent of people, most commonly around the age of 20. The majority of cases, according to previous longitudinal studies of high-risk populations, experience major depressive disorder (MDD) as an index mood episode prior to the first (hypo) manic episode. In addition, these studies indicated that it took an average of five years to receive a diagnosis of bipolar disorder (BD). The ideal time to identify and intervene is between the onset of symptoms and its complete development.

Brain plasticity is frequently cited as the cause of the better prognosis in paediatric stroke compared to adult stroke. We looked into the connection between linguistic prowess and language localization in paediatric stroke. 17 kids and teenagers with left- or right-sided ischemic stroke and 18 healthy controls underwent a battery of extensive neurolinguistic tests, and an fMRI language paradigm was used to measure each person's individual brain representation of language. Among the 17 stroke patients, 12 had language skills that were below average, and five had language performance issues. Right hemisphere regions homotopic to left hemisphere language regions showed higher activity in fMRI.