Journal of Textile Science & Engineering

Polylactic Glycolic Acid (PLGA) is most important polymer in biomedical applications because we can modify the degradation rate by copolymerization ratio, processing. The ideal scaffold should be three dimensional, highly porous, biodegradable and biocompatible without immune reaction or inflammation. In addition, it should have proper mechanical properties to support the growth of new tissue. Increased in the use of electrospinning nanofiber technique to create nanofiber scaffold for tissue engineering, as there are reports that these scaffolds successfully promote to cell matrix and cell-cell interactions with the cells of human body. Now days, success have been achieved in skin, bladder, airway, bone, kidney where tissue engineering construct has been successfully used.

PLGA synthesis done by convectional method, with study of various parameter such as time, temperature, monomer and catalyst ration. PLGA can be synthesized by polycondensation (convectional) method at 130°C, for 25 hours. Important characteristics such as melting temperature, glass transition temperature, and degradation temperature was determined by DSC and TGA analysis, it was obtained as 168.44°C, 55.76°C and 87.61°C respectively. Chemical structure was studied by FTIR and NMR. These results helped to study the effect of monomer, catalyst on reaction and determining the parameters for melt and electro spinning. Because of good biocompatibility and biodegradability, they can be used in various areas, such as long-term release systems and the tissue engineering.

Textile enterprise has protracted records of being thrifty with its resources; a massive share of useless waste remains produced every year. Commercially, fabric waste era is encouraged with the aid of using the manufacturing of fabric goods. The textile Industry makes use of first rate portions of non-renewable resources, comprising petroleum, extracted to manufacture garments which are used simplest for a moderate time frame and undergoes landfill or incineration. Wet processing approach that contain dyeing, finishing, printing, etc. initiate toxic emissions. Spinning of yarns and weaving/knitting of fabric most usually rely upon fossil power use, inflicting emissions consisting of CO and greenhouse emissions. Water use, toxic chemical compounds and waste are the principle environmental problems confronted with the aid of using the fabric enterprise. In this paper, it's far cautioned the opportunity approaches for land fill and incineration primarily based totally on upcycling and recycling of the fabric products.